Python AI agent frameworks (2026)
Agent frameworks and SDKs whose listings say they are built for Python. Here are all 9 from the AgentScout directory.
How we picked and ranked: tools are matched by category, the pricing each maker states and what each tool says it does. They are ranked by GitHub stars as recorded on each listing (link checks 2026-10-18); tools without a tracked repo follow, by listing maturity. No paid placements.
1. Agno
Python framework and runtime for building, running and managing multi-agent systems with memory, knowledge and tools.
Pricing (as stated): Open source + cloud · Mature
2. OpenAI Agents SDK (Python)
OpenAI's Python SDK for building multi-agent workflows; v0.23.0/0.23.1 released Oct 1-2.
Pricing (as stated): Open source · Mature, official SDK
3. Pydantic AI
Type-safe Python agent framework from the Pydantic team.
Pricing (as stated): Open source · Mature
4. Microsoft Agent Framework
Microsoft's framework for building and orchestrating agents and multi-agent workflows in Python and .NET.
Pricing (as stated): Open source · Mature
5. Strands Agents
Strands open-source SDK for building production agent harnesses in Python and TypeScript.
Pricing (as stated): Open source · Mature
6. Upsonic
Python framework for building autonomous AI agents.
Pricing (as stated): Open source · Mature
7. Genkit
Google's open-source framework for building agentic apps in JavaScript, Go, Dart and Python.
Pricing (as stated): Open source · Mature
8. Marvin
Python library from Prefect for building AI agents and structured LLM workflows.
Pricing (as stated): Open source · Mature
9. Langroid
Python framework for multi-agent programming with LLMs.
Pricing (as stated): Open source · Active
FAQ
What are the best Python AI agent frameworks?
Ranked by tracked GitHub stars, the top Python AI agent frameworks in our directory are Agno, OpenAI Agents SDK (Python), Pydantic AI, Microsoft Agent Framework, Strands Agents. Stars measure popularity, not fit, so compare a few against your own task.
How many Python AI agent frameworks does AgentScout list?
9 tools match. This page shows the top 9. Pricing mix on this page: Open source (8), Open source + cloud (1).
How much do these tools cost?
Pricing is what each maker states on their site. Open-source tools are free to self-host but may need a paid model API key or offer paid cloud plans; freemium tools have a free plan with limits. Check each official site.
Where can I see every tool for building AI agents?
Our task page lists all 137 tools we match to building AI agents.
Related: All tools for building AI agents · Best AI Agent Frameworks · frameworks (9)
Similar searches: Open-source AI agent frameworks · TypeScript and JavaScript AI agent frameworks · Multi-agent frameworks
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Facts come from our directory listings; pricing is as each maker states it and can change. Check official sites before you choose.